Broccoli builds a guard of honour along the gut highway

broccoli building gut defences

I constantly need reminding of the health benefits of broccoli, because in terms of taste, broccoli has a very nasty bite (for me).

Fortunately, the scientific literature is peppered with broccoli endorsements. Researchers from The Babraham Institute in Cambridge, have just demonstrated that those little broccoli florets are actively involved in creating a guard of honour along the gut highway.

Gut defenders need pedestals to stand on

Intra-epithelial lymphocytes (IELs) are a type of immune cell, which hovers just beneath the layer of cells which line both inner and outer body surfaces.

In this strategic position they help to keep things out and should the barrier be breached, patch things up.

IELs need help “standing” in position. A special protein platform known as the aryl hydrocarbon receptor (AhR), anchors them in place.

Broccoli lays the foundation for this guard of honour

Something in the broccoli family of vegetables, is responsible for laying down these aryl hydrocarbon receptor bases.

When cruciferous vegetables are absent from the diet of mice – few of the platforms are laid out, with nothing to stand on, the IEL protectors end up being few and far between.

Security is compromised and the microbes that live just beyond the border, begin to cause TROUBLE.

Defence system becomes dicey

With 70 to 80 % of the IELs failing to report for duty, the GUT defence system is weakened.

For mice this means

  • lower levels of antimicrobial proteins,
  • heightened immune activation and
  • increased susceptibility to injury

Of mice and men

The current research is in mice, NOT MEN.

At this stage, it is clear mice should be eating greens………. but what works for mice, probably works for man as well.

Broccoli chemicals

A bite of broccoli, bitter as it may be, is already full of beneficial chemicals, besides doses of vitamins E, C, K,  iron, zinc, selenium and a couple of polyphenols,  broccoli florets are loaded with sulforaphane.  This phytonutrient is a powerful anti-inflammatory with proven cancer fighting powers and it survives even if broccoli turns to mush.

Based on these findings in mice, broccoli contains another influential ingredient, which helps keep the sentinels serving on the gut border at their post so the immune system functions at its best.

So boil up a pot of broccoli for dinner tonight – it really is good for you !

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation. Cell (2011) 147(3): 629-640.  Ying Li, Silvia Innocentin, David R. Withers, Natalie A. Roberts, Alec R. Gallagher, Elena F. Grigorieva, Christoph Wilhelm, Marc Veldhoen.
 

Interested in learning more about the chemical impact of the food you eat ?

Subcribe to E-spoons, to get e-mail updates once a month to learn how to keep your body chemistry balanced to avoid / tame the big killers – diabetes, heart disease and cancer.

NOTE : Privacy & spam policy. Spoonful of Science will not rent, trade or sell the e-mail list to anyone. You can unsubscribe at any time by following the unsubscribe link.

Know someone who will find this post useful ? Share it on facebook, linkedin, twitter

Further reading

bacteria disguised as self broccoli and breast milk bacteria hiding among the sugar covered cells
How does your body know who the good bacteria are ?  How to raise a child that loves vegetables  Why infections are difficult to overcome in diabetics

The 7 Big Spoons™…. are master switches that turn health on.

balance eicosanoids rein in insulin dial down stress sleep vitamin D microflora think
Balance Eicosanoids Rein in insulin Dial down stress Sleep ! Increase Vit D Culivate microflora Think champion

Hire Dr Sandy from a Spoonful of Science to be the keynote speaker at your next event.

Did you learn something new or do you have a different perspective ? I’d love to hear from you so post me a comment below…..

This entry was posted in Phytonutrients and tagged , , , , , . Bookmark the permalink. Follow any comments here with the RSS feed for this post. Post a comment or leave a trackback: Trackback URL.

Post a Comment

Your email is never published nor shared. Required fields are marked *

*
*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>