Unlocking vitamin B12 from your dinner takes an acidic twist

acid is the key to unlock the vitamin B12 packageSo, you’re a serious carnivore – you’ve just enjoyed a piece of steak. Hanging onto your bites of animal protein, is the cobalamin (vitamin B12) package.

It is not loosely attached, it is locked down tight.

The key to wrenching the package off the piece of meat is hydrochloric acid. The acid is able to pop the lock and allow the vitamin B12 package to be slipped off the meat, so it can be transferred to Intrinsic Factor, with the help of a protein that goes by the name, R.

Anything that interferes with the acidity in the stomach – blocks this transfer process.

NOTE : Just getting older seems to bring on lower acid levels, so elderly folks are a lot more likely to end up being short of vitamin B12. Vitamin B12 shortages have been implicated in the thinking troubles associated with aging.

Where has all the acid gone ?

Inflammation in the GUT, brought on by specific foods, resident bugs or unrelenting stress, often causes acid troubles, which manifest as agonizing INDIGESTION i.e. a feeling that your belly is ON FIRE.

People suffering from TOO MUCH ACID, feel compelled to put out the fire, one way or another.

A multitude of options exist, from

  • avoiding the offending foods, such as hot chilli stew
  • glugging down something cool, like a glass of milk
  • to sucking on a Rennies® or swigging down some Gavascon®, products available as part of over-the-counter antacids formulations
  • to swallowing prescription meds, such as a proton pump inhibitors (PPIs) or an anti-histamine

The medications bring relief, BECAUSE they interfere with acid production.

But in addition to upsetting the gut microflora, blocking acid production on a routine basis, can contribute to vitamin B12 shortages because, the acid is facilitating the final hand over of the vitamin B12 package.

The final hand over

The acid pries the package off the animal protein, R protein then helps to get the vitamin B12 molecule attached to Intrinsic Factor – who is responsible for getting the vitamin B12 across the gastrointestinal border. Intrinsic factor achieves this objective by hooking up with it’s special transporter located in the small intestine.

If intrinsic factor doesn’t arrive on the scene, the R protein has no choice but to drop the package, which then gets swept out of the gut. The valuable package then slips out the body, when you go to the loo, to do a number 2.

Intrinsic Factor a gentle giant

Intrinsic factor is a shy character. Only a few molecules venture out, each time you eat.

If you’ve eaten a plateful of liver, loaded with cobalamin or swallowed a mega-dose of a crystalline vitamin B12 supplement, a very small amount of the vitamin B12 will end up being transported into the liver.

Experts think at any given “meal” – the maximum amount that will be absorbed from food is around 1 – 2 ug. This is very little, but it isn’t a problem if you’re eating animal foods on a regular basis and the acid system of the stomach is working efficiently. Your body should have a stash of the stuff and you only need a little bit everyday.

Except…. when Intrinsic Factor goes AWOL.  Continued tomorrow….

Vitamin B12 in Health and Disease. Nutrients (2010) 2, 299-316. Fiona O’Leary and Samir Samman.

Interested in learning more about better body chemistry ? 

Subcribe to E-spoons, to get e-mail updates once a month to learn how to keep your body chemistry balanced so you can perform at your best. 

NOTE : Privacy & spam policy. Spoonful of Science will not rent, trade or sell the e-mail list to anyone. You can unsubscribe at any time by following the unsubscribe link.

Know someone who will find this post useful ? Share it on facebook, linkedin, twitter

Further reading

cucumber hiding vitamins under his jacket cells lining stomach being burnt because of aspirin old bee in a rocking chair
That salad is just lettuce leaves without the right dressing Watch out, aspirin burns holes in your stomach A bee fix for an aging brain

The 7 Big Spoons™…. are master switches that turn health on.

balance eicosanoids rein in insulin dial down stress sleep vitamin D microflora think
Balance Eicosanoids Rein in insulin Dial down stress Sleep ! Increase Vit D Culivate microflora Think champion

Hire Dr Sandy from a Spoonful of Science to be the keynote speaker at your next event.

Did you learn something new or do you have a different perspective ? I’d love to hear from you so post me a comment below

This entry was posted in vitaminb12 and tagged , , , , , , , , , , , , , , , . Bookmark the permalink. Follow any comments here with the RSS feed for this post. Post a comment or leave a trackback: Trackback URL.

One Comment

  1. Manaka Niita says:

    Very interesting insights on how to efficiently unlock vitamin b12 nutrient from its sources. Having this tip known to me, it’s much easier to get an ample amount of b12 in the body.

Post a Comment

Your email is never published nor shared. Required fields are marked *


You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>